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Overview 
Asthma affects over 300 million individuals worldwide, and between 5-10% of Americans, making it one of the most prevalent common chronic diseases. Insight into medical biology provides insight into disease mechanisms. As such, asthma research is shifting from a broad perspective to a narrower focus that includes cellular profiles, protein analysis and genetic markers combined with clinical measures. This symposium will address underlying pathophysiology of asthma, current issues related to heterogeneity and novel therapies. 

Objectives 

• Explain how the asthmatic airway epithelium contributes to disease 
• Recognize different inflammatory pathways by which asthma develops and identify in those pathways therapeutic targets in use or in development 
• Discuss the heterogeneity in asthmatic patients and illustrate how to use various biomarkers to begin to personalize therapy 

Registration 
Registration fee* includes continental breakfast, refreshment break, and lunch: 

Physicians – $150 
Nurses/PAs/Allied Health Professionals – $100 
Residents/Fellows/Students† – Complimentary, registration required 
Exhibitors - $2,000 
*All cancellations must be received in writing (or via e-mail) at least one week prior to the start of the conference to receive a refund. Any requests for refunds received after this date, or by telephone, will not be honored. 

†A letter of verification from department head must accompany registration. Letter should be sent separately to Yale CME at the address below. You may also e-mail a pdf copy of your verification letter to cme@yale.edu. 

If paying via check, include conference name in the memo, make check payable to Yale University and send to: 

Center for Continuing Medical Education 
Yale School of Medicine 
333 Cedar Street 
PO Box 208052 
New Haven, CT 06520-8052 

*Online registration will close the afternoon before the program. Onsite registrants accepted. 

Accreditation 
Accreditation Statement 

The Yale School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. 

Designation Statement 

The Yale School of Medicine designates this live activity for a maximum of 5.5 AMA PRA Category 1 Credits(TM). Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Disclosure Policy 

It is the policy of Yale School of Medicine, Continuing Medical Education, to ensure balance, independence, objectivity and scientific rigor in all its educational programs. All faculty participating as speakers in these programs are required to disclose any relevant financial relationship(s) they (or spouse or partner) have with a commercial interest that benefits the individual in any financial amount that has occurred within the past 12 months; and the opportunity to affect the content of CME about the products or services of the commercial interests. The Center for Continuing Medical Education will ensure that any conflicts of interest are resolved before the educational activity occurs. 

Directions 

This conference will be held at the Anlyan Center for Medical Research and Education, 1st Floor Auditorium, 300 Cedar Street, New Haven, CT. 

From I-95 North or South: Leave I-95 at Exit 47 (Downtown New Haven/Rte 34). This puts you onto an exit expressway. Merge onto CT-34 W via Exit 1 toward Downtown New Haven. Follow the short expressway, and merge into the left lane after the traffic light; the entrance to the parking garage will be on your left. Visitor parking available in Air Rights Garage (see parking information below) or use the Howard Avenue Garage (see below). 

From I-91 South: Leave I-91 South at Exit 1 (Downtown New Haven/Rte 34). This exit puts you onto a short expressway. Follow the short expressway, and merge into the left lane after the traffic light; the entrance to the garage will be on your left. Visitor parking available in the Air Rights Garage (see parking information below) or use the Howard Avenue Garage (see below). 

Parking Information 

The Air Rights Garage is open 24 hours a day and located between North and South Frontage roads, straddling York St. Rates: 0-3 hours - $3 per hour, 4-10 hours - $12 flat rate, 10-24 hours - $18 flat rate. Walking from the garage, head southwest on York Street toward Cedar Street, for approximately 80 feet. Turn left onto Cedar Street. Continue down Cedar Street until you arrive at the intersection of Congress Avenue and Cedar Street. The Anlyan Center will be across the street. 

Howard Avenue Garage, 800 Howard Ave, New Haven, CT 06519, opposite from Yale-New Haven Hospital and next to the Yale Physicians Building. The garage is located in between the streets of Davenport and Congress. It is open from 6 am to 9 pm during week days only. Rates: $3 per hour. Walking from the garage, head south toward Congress Avenue for approximately 300 feet. Turn left onto Congress Avenue and continue walking until you arrive at the intersection of Congress Avenue and Cedar Street. The Anlyan Center is located at this intersection. 

The New Haven Parking Authority, (203) 946-8936, can provide further assistance for rate information.